Monkeypox (MPV): Vaccination

Expanded Eligibility

Eligibility has been expanded! Now anyone of any sexual orientation or gender identity who is at risk for MPV can get vaccinated. See below for details, including recommendations on who should get vaccinated.

First & Second Dose Appointments and Walk-Ins Available

There are first and second dose appointments available. All City-run sites also accept walk-ins.

If you are eligible, you can make an appointment or find a vaccination site by clicking on the button below, or by calling 877-VAX-4NYC (877-829-4692).


 

You should get a second dose at least 28 days after your first dose.

You will start to build protection in the days and weeks after your first dose, but you will not have full immunity from the vaccine until two weeks after the second dose. You can get a second dose intradermally even if you got your first dose subcutaneously.

If you have had MPV, then you likely have some protection against another infection and are currently not eligible for a first or second dose of the vaccine at this time.

Intradermal Injections

To make more doses available, the federal government has mandated the vaccine now be given intradermally — into an outer layer of skin (dermis). This method allows us to get four to five times more doses from the same amount of supply. Evidence has shown this approach will provide similar protection as subcutaneous injections, which are made into the deepest layer of skin.

Due to potential differences in side effects for the two injection methods, the CDC recommends people who have had keloid scars receive a subcutaneous injection. The risk for these types of reactions is higher for people with darker skin. Those who have a history of keloid formation will be allowed to request a subcutaneous injection at the vaccination site.


Getting vaccinated for MPV can reduce your chance of getting MPV, and it can reduce symptoms if you do get it. Eligible New Yorkers who may have been recently exposed to MPV can get the JYNNEOSTM vaccine.

We are still learning about how well the vaccine can protect you. Even after getting vaccinated, you should still take precautions, especially if you are at high risk for severe illness from MPV.


Eligibility

Eligibility for MPV vaccination may change as the outbreak evolves and based on vaccine supply. Vaccination is free and available regardless of immigration status or residency.

NEW: Eligibility for MPV vaccination has expanded. The following people are eligible to be vaccinated in NYC:

  • People of any sexual orientation or gender identity who have or may have multiple or anonymous sex partners, or participate or may participate in group sex
  • People of any sexual orientation or gender identity whose sex partners are eligible per the criteria above
  • People who know or suspect they have been exposed to the MPV in the last 14 days
  • Anyone else who considers themselves to be at risk for MPV through sex or other intimate contact.

NOTE: People who are breastfeeding or pregnant who are otherwise eligible for vaccination can get vaccinated. For more information, see the JYNNEOS FAQ.

If you have had MPV, then you likely have some protection against another infection and are currently not eligible to get a first or second dose.

People with certain allergies to vaccine ingredients or chicken or egg protein should talk to a health care provider to confirm if they should get the vaccine. If you do not have a provider, call 311 or search the NYC Health Map.


Who Should Get Vaccinated Now

The current MPV outbreak has affected some populations more than others. In addition, the risk of getting MPV is higher among people who engage in certain activities or have certain health conditions. Based on this, the JYNNEOS vaccine is recommended for people who meet the above eligibility criteria and:

  • Are men whose sex partners are men (cisgender or transgender), transgender women or gender nonconforming or nonbinary individuals; especially those who have been diagnosed with a sexually transmitted infection (STI) in the past 6 months
  • Are transgender, gender non-conforming or gender non-binary, especially those who have been diagnosed with an STI in the past 6 months
  • Are cisgender women whose sex partners are men who have sex with men or who are transgender, gender non-conforming or gender non-binary
  • Participate or may participate in sex parties or other events where there is minimal clothing and direct, frequent, or prolonged skin-to-skin contact
  • People who have had or anticipate having sex at a commercial sex venue or sex in association with a large public event
  • Are taking HIV pre-exposure prophylaxis (PrEP)
  • Are living with HIV
  • Sex workers, erotic workers and anyone engaging in survival sex or any other types of transactional sex (including sex in exchange for money, food, shelter or other goods) of any sexual orientation or gender identity

Getting Multiple Vaccines at Once

You can get the JYNNEOS vaccine at the same time as most vaccines, including the flu, human papilloma virus (HPV), hepatitis A, hepatitis B, meningococcal and herpes zoster (shingles) vaccines.

You can get the JYNNEOS vaccine before, after, or at the same time as COVID-19 vaccines too. However, people at increased risk of myocarditis (inflammation of the heart), particularly males ages 12-39, can consider waiting four weeks between getting the JYNNEOS and COVID-19 vaccines. This is because there is a rare risk of developing myocarditis after COVID-19 vaccination. And while JYNNEOS clinical trials did not show an increased risk of myocarditis following vaccination, it is possible there is a risk.

If you know you were recently exposed to MPV, you should not delay getting the JYNNEOS vaccine, even if you recently got a COVID-19 vaccine.

For others, in deciding whether to delay getting either vaccine, consider your risk of exposure and risk of severe illness from COVID-19 and MPV. Talk to your health care provider if you have questions about timing of vaccination.

Side Effects

Common side effects of the JYNNEOS vaccine include tiredness, headache and muscle pain. There may also be redness, swelling, soreness and itchiness where you received the injection. Generally, the injection site side effects from an intradermal injection are worse and last longer than those from a subcutaneous injection.

Intradermal injections can result in long-term or permanent scarring, discoloration and thinning of the skin at the injection site. The risk for these types of reactions is higher for people with darker skin.

People will be asked at the vaccination site whether they have a history of keloid scars, and those who do will be offered subcutaneous administration.


How to Get Vaccinated

First- and second-dose appointments are now available. Walk-in vaccinations for first and second doses are also available at all City-run sites. You can get a second dose at least 28 days after your first dose.

If you are eligible, you can make an appointment or find a vaccination site by clicking on the button below, or by calling 877-VAX-4NYC (877-829-4692).


 

You must bring one of the following to your vaccination appointment:

  • Driver’s license or non-driver ID
  • IDNYC
  • Birth certificate issued by a state or local government
  • Current U.S. passport or valid foreign passport
  • Permanent resident card
  • Certificate of Naturalization or Citizenship
  • Life insurance policy with birthdate
  • Marriage certificate with birthdate

For more information about MPV, call 311.

Consent for Minors

Minors ages 17 years and younger may receive the JYNNEOS vaccine.

Most minors must have parental, guardian or legal custodian consent to receive the vaccine. Certain minors have the right to consent to their own care, such as married minors, minors who are parents or pregnant and minors in the military.

For minors 16 or 17 years of age, the parent or guardian should provide consent either in person or by phone, at the time of the vaccine appointment. The parent or guardian can provide a written statement of consent at City-run vaccination locations if they are not available by phone. The written statement must include the minor's name and date of birth, and the parent or guardian's name, phone number and signature.

For minors 15 years of age or younger, an adult caregiver must accompany the minor. If the adult caregiver is not the parent or guardian, the adult caregiver should be designated by the parent or guardian. The parent or guardian must still provide consent by phone at the time of the appointment or by written statement. The written statement must include the minor's name and date of birth, and the parent or guardian's name, phone number and signature. Some providers require additional documentation in the medical record that provides consent for minors under 15 to be seen without the parent or guardian.